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CD247 抗体 (pTyr142)

This anti-CD247 antibody is a 兔 多克隆 antibody detecting CD247 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7225868
发货至: 中国

Quick Overview for CD247 抗体 (pTyr142) (ABIN7225868)

抗原

See all CD247 抗体
CD247 (CD247 Molecule (CD247))

适用

  • 92
  • 40
  • 17
  • 4
  • 1
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  • 1
  • 1
人, 小鼠, 大鼠, 猴

宿主

  • 75
  • 14
  • 5
  • 1

克隆类型

  • 63
  • 32
多克隆

标记

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  • 3
  • 3
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  • 2
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  • 1
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This CD247 antibody is un-conjugated

应用范围

  • 60
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  • 19
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  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 13
    • 9
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    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr142

    原理

    CD3 ζ (phospho Tyr142) Polyclonal Antibody

    特异性

    Phospho-CD3 ζ (Y142) Polyclonal Antibody detects endogenous levels of CD3 ζ protein only when phosphorylated at Y142.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human CD3 zeta Phospho-Tyr142

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CD247 (CD247 Molecule (CD247))

    别名

    CD3 zeta

    背景

    Rabbit Anti-CD3 ζ (phospho Tyr142) Polyclonal Antibody,CD247, CD3Z, T3Z, TCRZ, T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD antigen CD247,The protein encoded by CD247 (CD247 Molecule) is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for CD247.,T-cell surface glycoprotein CD3 zeta chain

    分子量

    observerd band 20kDa

    基因ID

    919

    UniProt

    P20963

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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