CD158f2 (AA 130-210) 抗体
The 兔 多克隆 anti-CD158f2 antibody is suitable to detect CD158f2 in samples from 人. It has been validated for ELISA, WB 和 IF.
产品编号 ABIN7223410
发货至:
中国
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Quick Overview for CD158f2 (AA 130-210) 抗体 (ABIN7223410)
抗原
CD158f2
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Immunofluorescence (IF)
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抗原表位
- AA 130-210
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原理
- CD158f2 Polyclonal Antibody
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特异性
- CD158f2 Polyclonal Antibody detects endogenous levels of CD158f2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CD158f2 at AA range: 130-210
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CD158f2
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背景
- Rabbit Anti-CD158f2 Polyclonal Antibody,KIR2DL5B, CD158F, CD158F2, KIR2DL5, KIR2DLX, Killer cell immunoglobulin-like receptor 2DL5B, CD158 antigen-like family member F2, Killer cell immunoglobulin-like receptor 2DLX, CD antigen CD158f2,Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.,Killer cell immunoglobulin-like receptor 2DL5B
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分子量
- observerd band 40kDa
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基因ID
- 553128
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UniProt
- Q8NHK3
抗原
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