CNOT7 抗体 (AA 10-90)
Our Local Distributor
北京 101111
Quick Overview for CNOT7 抗体 (AA 10-90) (ABIN7214270)
抗原
See all CNOT7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-90
-
原理
- CNOT7 Polyclonal Antibody
-
特异性
- CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the N-terminal region of human CNOT7 at AA range: 10-90
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
-
别名
- CNOT7
-
背景
- Rabbit Anti-CNOT7 Polyclonal Antibody,CNOT7, CAF1, CCR4-NOT transcription complex subunit 7, BTG1-binding factor 1, CCR4-associated factor 1, CAF-1,CCR4-NOT transcription complex subunit 7 encoded by CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of CNOT7 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.,CCR4-NOT transcription complex subunit 7
-
分子量
- observerd band 36kDa
-
基因ID
- 29883
-
UniProt
- Q9UIV1
-
途径
- Ribonucleoprotein Complex Subunit Organization
抗原
-