CEBPA 抗体 (pSer21)
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Quick Overview for CEBPA 抗体 (pSer21) (ABIN7213230)
抗原
See all CEBPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer21
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原理
- C/EBP α (phospho Ser21) Polyclonal Antibody
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特异性
- Phospho-C/EBP α (S21) Polyclonal Antibody detects endogenous levels of C/EBP α protein only when phosphorylated at S21.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human C/EBP alpha Phospho-Ser21
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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别名
- C/EBP alpha
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背景
- Rabbit Anti-C/EBP α (phospho Ser21) Polyclonal Antibody,CEBPA, CCAAT/enhancer-binding protein alpha, C/EBP alpha,This intronless gene (CEBPA) encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein (CCAAT/enhancer binding protein alpha) functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of CEBPA is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.,CCAAT
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分子量
- observerd band 45kDa
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基因ID
- 1050
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UniProt
- P49715
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途径
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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