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Cathepsin D 抗体 (Cleaved-Gly65)

The 兔 多克隆 anti-Cathepsin D antibody (ABIN7212454) specifically detects Cathepsin D in WB 和 ELISA. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN7212454
发货至: 中国
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Quick Overview for Cathepsin D 抗体 (Cleaved-Gly65) (ABIN7212454)

抗原

See all Cathepsin D (CTSD) 抗体
Cathepsin D (CTSD)

适用

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人, 猴

宿主

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克隆类型

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多克隆

标记

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This Cathepsin D antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 20-100, Cleaved-Gly65

    原理

    Cleaved-Cathepsin D LC (G65) Polyclonal Antibody

    特异性

    Cleaved-Cathepsin D LC (G65) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin D LC protein resulting from cleavage adjacent to G65.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Cathepsin D LC at AA range: 20-100

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Cathepsin D (CTSD)

    别名

    Cathepsin D LC

    背景

    Rabbit Anti-Cleaved-Cathepsin D LC (G65) Polyclonal Antibody,CTSD, CPSD, Cathepsin D,CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.,Cathepsin D

    分子量

    observerd band 17kDa

    基因ID

    1509

    UniProt

    P07339

    途径

    Peptide Hormone Metabolism
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