CTSC 抗体 (Cleaved-Arg394)
Our Local Distributor
北京 101111
Quick Overview for CTSC 抗体 (Cleaved-Arg394) (ABIN7212450)
抗原
See all CTSC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 320-400, Cleaved-Arg394
-
原理
- Cleaved-Cathepsin C HC (R394) Polyclonal Antibody
-
特异性
- Cleaved-Cathepsin C HC (R394) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin C HC protein resulting from cleavage adjacent to R394.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human Cathepsin C HC at AA range: 320-400
-
亚型
- IgG
-
-
anti-Cathepsin C (CTSC) antibody
CTSC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Cathepsin C (CTSC) (AA 231-463) antibodyCTSC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (C-Term), (cleaved) antibodyCTSC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 25-134) antibodyCTSC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 238-252) antibodyVerified CTSC 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (Arg394), (cleaved) antibodyCTSC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 1-463) antibodyCTSC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 1-463) antibodyCTSC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 185-234) antibodyCTSC 适用: 人, 小鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 231-462) antibodyCTSC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- CTSC (Cathepsin C (CTSC))
-
别名
- Cathepsin C HC
-
背景
- Rabbit Anti-Cleaved-Cathepsin C HC (R394) Polyclonal Antibody,CTSC, CPPI, Dipeptidyl peptidase 1, Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, DPP-I, DPPI, Dipeptidyl transferase,CTSC encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. Cathepsin Crequires chloride ions for activity and can degrade glucagon. Defects in the cathepsin C have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.,Dipeptidyl peptidase 1
-
分子量
- observerd band 27kDa
-
基因ID
- 1075
-
UniProt
- P53634
抗原
-
