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COMT 抗体 (AA 30-110)

This 兔 多克隆 anti-COMT antibody specifically detects COMT in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7219562
发货至: 中国
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Quick Overview for COMT 抗体 (AA 30-110) (ABIN7219562)

抗原

See all COMT 抗体
COMT (Catechol-O-Methyltransferase (COMT))

适用

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宿主

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克隆类型

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多克隆

标记

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This COMT antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 30-110

    原理

    COMT Polyclonal Antibody

    特异性

    COMT Polyclonal Antibody detects endogenous levels of COMT protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human COMT at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    COMT (Catechol-O-Methyltransferase (COMT))

    别名

    COMT

    背景

    Rabbit Anti-COMT Polyclonal Antibody,COMT, Catechol O-methyltransferase,Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.,Catechol O-methyltransferase

    分子量

    observerd band 30kDa

    基因ID

    1312

    UniProt

    P21964

    途径

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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