CARD11 抗体 (AA 10-90)
Our Local Distributor
北京 101111
Quick Overview for CARD11 抗体 (AA 10-90) (ABIN7213938)
抗原
See all CARD11 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-90
-
原理
- CARD 11 Polyclonal Antibody
-
特异性
- CARD 11 Polyclonal Antibody detects endogenous levels of CARD 11 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the N-terminal region of human CARD 11 at AA range: 10-90
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
-
别名
- CARD 11
-
背景
- Rabbit Anti-CARD 11 Polyclonal Antibody,CARD11, CARMA1, Caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 1, Carma 1,The protein encoded by CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.,Caspase recruitment domain-containing protein 11
-
分子量
- observerd band 130kDa
-
基因ID
- 84433
-
UniProt
- Q9BXL7
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
-