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RORB 抗体 (AA 385-470) (Biotin)

RORB 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN715873
发货至: 中国
  • 抗原 See all RORB 抗体
    RORB (RAR-Related Orphan Receptor B (RORB))
    抗原表位
    • 14
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 385-470
    适用
    • 48
    • 27
    • 26
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 54
    • 8
    克隆类型
    • 54
    • 8
    多克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RORB antibody is conjugated to Biotin
    应用范围
    • 47
    • 22
    • 19
    • 13
    • 13
    • 9
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RORB
    亚型
    IgG
    Top Product
    Discover our top product RORB Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    RORB (RAR-Related Orphan Receptor B (RORB))
    别名
    ROR beta (RORB 产品)
    别名
    RORB antibody, Nr1f2 antibody, LOC100226267 antibody, NR1F2 antibody, ROR-BETA antibody, RZR-BETA antibody, RZRB antibody, bA133M9.1 antibody, nr1f2 antibody, rzrb antibody, sb:eu943 antibody, RZR-beta antibody, Rorbeta antibody, RAR related orphan receptor B antibody, RAR-related orphan receptor B antibody, RAR-related orphan receptor beta antibody, RORB antibody, Rorb antibody, rorb antibody
    背景

    Synonyms: NR1F2, Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, ROR BETA, Rorb, RORB_HUMAN, RZR BETA, RZRB.

    Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)

    基因ID
    6096
    UniProt
    Q92753
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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