Caspase 4 p20 (AA 40-120), (Cleaved-Gln81) 抗体
This 兔 多克隆 antibody specifically detects Caspase 4 p20 in WB, ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7202048
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Caspase 4 p20 (AA 40-120), (Cleaved-Gln81) 抗体 (ABIN7202048)
抗原
Caspase 4 p20
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
-
-
抗原表位
- AA 40-120, Cleaved-Gln81
-
原理
- Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody
-
特异性
- Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-4 p20 protein resulting from cleavage adjacent to Q81.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human Caspase-4 p20 at AA range: 40-120
-
亚型
- IgG
-
-
anti-Caspase 4 p20 (cleaved), (Gln81) antibody
适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4 p20 (Center) antibody适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Caspase 4 p20
-
别名
- Caspase-4 p20
-
背景
- Rabbit Anti-Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody,CASP4, ICH2, Caspase-4, CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX,CASP4 encodes caspase 4 that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, CASP4 induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.,Caspase-4
-
基因ID
- 837
-
UniProt
- P49662
抗原
-
You are here:
