Caspase 2 p18 抗体 (Cleaved-Gly170)
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北京 101111
Quick Overview for Caspase 2 p18 抗体 (Cleaved-Gly170) (ABIN7212436)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-200, Cleaved-Gly170
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原理
- Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody
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特异性
- Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to G170.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Caspase-2 p18 at AA range: 120-200
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亚型
- IgG
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anti-Caspase 2 p18 (cleaved), (Gly170) antibody
适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2 p18 (Cleaved-Gly170) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2 p18 (Center) antibody适用: 人, 小鼠, 大鼠, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Caspase 2 p18
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别名
- Caspase-2 p18
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背景
- Rabbit Anti-Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody,CASP2, ICH1, NEDD2, Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1,CASP2 encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. Caspase 2 may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,Caspase-2
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分子量
- observerd band 18 or 35kDa
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基因ID
- 835
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UniProt
- P42575
抗原
-
