CILP 抗体
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北京 101111
Quick Overview for CILP 抗体 (ABIN7227908)
抗原
See all CILP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CILP1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CILP1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human CILP1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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别名
- CILP1
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背景
- Rabbit Anti-CILP1 Polyclonal Antibody,Cartilage intermediate layer protein 1, CILP-1, Cartilage intermediate-layer protein,Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. CILP encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.,CILP1
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分子量
- observerd band 130kDa
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基因ID
- 8483
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UniProt
- O75339
抗原
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