CLCF1 抗体 (AA 171-220)
Quick Overview for CLCF1 抗体 (AA 171-220) (ABIN7230036)
抗原
See all CLCF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-220
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原理
- NNT-1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of NNT-1
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human NNT-1 protein at AA range: 171-220
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亚型
- IgG
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anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 88-190) antibody
CLCF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) antibodyCLCF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-225) antibodyCLCF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-178) antibodyCLCF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) antibodyCLCF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 29-225) antibodyCLCF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 1-225) antibodyCLCF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
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别名
- NNT-1
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背景
- Rabbit Anti-NNT-1 Polyclonal Antibody,Cardiotrophin-like cytokine factor 1, B-cell-stimulating factor 3, BSF-3, Novel neurotrophin-1, NNT-1,CLCF1 is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,NNT-1
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基因ID
- 23529
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UniProt
- Q9UBD9
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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