CPB2 抗体 (AA 290-370)
Quick Overview for CPB2 抗体 (AA 290-370) (ABIN7219614)
抗原
See all CPB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-370
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原理
- TAFI Polyclonal Antibody
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特异性
- TAFI Polyclonal Antibody detects endogenous levels of TAFI protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human TAFI at AA range: 290-370
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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别名
- TAFI
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背景
- Rabbit Anti-TAFI Polyclonal Antibody,CPB2, Carboxypeptidase B2, Carboxypeptidase U, CPU, Plasma carboxypeptidase B, pCPB, Thrombin-activable fibrinolysis inhibitor, TAFI,Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The carboxypeptidase B2 encoded by CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for CPB2 and its promoter region. Alternate splicing results in multiple transcript variants.,Carboxypeptidase B2
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分子量
- observerd band 48kDa
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基因ID
- 1361
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UniProt
- Q96IY4
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途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
抗原
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