CIC 抗体 (AA 550-630)
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Quick Overview for CIC 抗体 (AA 550-630) (ABIN7227904)
抗原
See all CIC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 550-630
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原理
- CIC Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CIC protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human CIC protein at AA range: 550-630
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亚型
- IgG
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anti-Capicua Homolog (CIC) (N-Term) antibody
CIC 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) (AA 1475-1560) antibodyCIC 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) (N-Term) antibodyCIC 适用: 小鼠, 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) (AA 174-203), (N-Term) antibodyCIC 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24284 unconjugated
anti-Capicua Homolog (CIC) (AA 177-207), (N-Term) antibodyCIC 适用: 小鼠, 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CIC (Capicua Homolog (CIC))
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别名
- CIC
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背景
- Rabbit Anti-CIC Polyclonal Antibody,Protein capicua homolog,CIC encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID: 6310), to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex. Mutations in this gene have been associated with olidogdendrogliomas (PMID: 21817013). In addition, translocation events resulting in gene fusions of this gene with both DUX4 (GeneID: 100288687) and FOXO4 (GeneID: 4303) have been associated with round cell sarcomas. There are multiple pseudogenes of this gene found on chromosomes 1, 4, 6, 7, 16, 20, and the Y chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.,CIC
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分子量
- observerd band 176kDa
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基因ID
- 23152
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UniProt
- Q96RK0
抗原
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