CAGE1 抗体 (AA 680-760)
Quick Overview for CAGE1 抗体 (AA 680-760) (ABIN7213916)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 680-760
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原理
- CAGE-1 Polyclonal Antibody
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特异性
- CAGE-1 Polyclonal Antibody detects endogenous levels of CAGE-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human CAGE-1 at AA range: 680-760
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亚型
- IgG
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anti-Cancer Antigen 1 (CAGE1) (C-Term) antibody
CAGE1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cancer Antigen 1 (CAGE1) (AA 2-100) antibodyCAGE1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-Cancer Antigen 1 (CAGE1) (C-Term) antibodyCAGE1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cancer Antigen 1 (CAGE1) (AA 2-35), (N-Term) antibodyCAGE1 适用: 人 WB 宿主: 兔 Polyclonal RB49261 unconjugated
anti-Cancer Antigen 1 (CAGE1) (AA 1-700) antibodyCAGE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cancer Antigen 1 (CAGE1) (AA 711-760) antibodyCAGE1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CAGE1 (Cancer Antigen 1 (CAGE1))
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别名
- CAGE-1
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背景
- Rabbit Anti-CAGE-1 Polyclonal Antibody,CAGE1, CTAG3, Cancer-associated gene 1 protein, CAGE-1, Cancer/testis antigen 3, CT3,CAGE (cancer-associated gene protein), also known as DEAD box protien 53 (DDX53) or DEAD box protein CAGE, belongs to the DEAD box helicase family. It contains one helicase ATP-binding domain, one helicase C-terminal domain and one KH domain. CAGE localizes to the nucleus and, in normal adult tissues, is exclusively expressed in testis but it has also been found in a wide variety of cancer tissues and cell lines. Overexpression of CAGE leads to the activation of FAK, ERK and p38 MAPK along with a reduction in reactive oxygen species (ROS). It is also responsible for inducing catalase activity and therefore enhancing cell motility. This suggests that CAGE may enhance the migration of cancer cells. In addition, hypomethylation of the CAGE promoter region is associated with tumor progression and may serve as a valuable marker in cancer diagnosis.,Cancer-associated gene 1 protein
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分子量
- observerd band 90kDa
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基因ID
- 285782
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UniProt
- Q8TC20
抗原
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