CREM 抗体 (AA 50-130)
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Quick Overview for CREM 抗体 (AA 50-130) (ABIN7219666)
抗原
See all CREM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-130
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原理
- Rabbit Anti-CREM Polyclonal Antibody
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特异性
- CREM Polyclonal Antibody detects endogenous levels of CREM protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human CREM at AA range: 50-130
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- CREM (CAMP Responsive Element Modulator (CREM))
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别名
- CREM
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背景
- CREM, cAMP-responsive element modulator, Inducible cAMP early repressor, ICERCREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
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分子量
- 34kD
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基因ID
- 1390
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UniProt
- Q03060
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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