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CAPN10 抗体 (N-Term)

This anti-CAPN10 antibody is a 兔 多克隆 antibody detecting CAPN10 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7219246
发货至: 中国

Quick Overview for CAPN10 抗体 (N-Term) (ABIN7219246)

抗原

See all CAPN10 抗体
CAPN10 (Calpain 10 (CAPN10))

适用

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宿主

  • 23

克隆类型

  • 23
多克隆

标记

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This CAPN10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 5
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    N-Term

    原理

    Calpain 10 Polyclonal Antibody

    特异性

    Calpain 10 Polyclonal Antibody detects endogenous levels of Calpain 10 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human Calpain 10

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CAPN10 (Calpain 10 (CAPN10))

    别名

    Calpain 10

    背景

    Rabbit Anti-Calpain 10 Polyclonal Antibody,CAPN10, KIAA1845, Calpain-10, Calcium-activated neutral proteinase 10, CANP 10,Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. CAPN10 encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. CAPN10 is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.,Calpain-10

    分子量

    observerd band 75kDa

    基因ID

    11132

    UniProt

    Q9HC96

    途径

    Positive Regulation of Peptide Hormone Secretion
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