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Caldesmon 抗体 (pSer789)

The 兔 多克隆 anti-Caldesmon antibody is suitable to detect Caldesmon in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA, IF 和 IHC (p).
产品编号 ABIN7213324
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Caldesmon 抗体 (pSer789) (ABIN7213324)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Caldesmon antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer789

    原理

    Caldesmon (phospho Ser789) Polyclonal Antibody

    特异性

    Phospho-Caldesmon (S789) Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at S789.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Caldesmon Phospho-Ser789

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    Caldesmon

    背景

    Rabbit Anti-Caldesmon (phospho Ser789) Polyclonal Antibody,CALD1, CAD, CDM, Caldesmon, CDM,CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction. Alternative splicing of CALD1 results in multiple transcript variants encoding distinct isoforms.,Caldesmon

    分子量

    observerd band 80kDa

    基因ID

    800

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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