Cadherin 7 抗体 (AA 620-700)
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Quick Overview for Cadherin 7 抗体 (AA 620-700) (ABIN7213912)
抗原
See all Cadherin 7 (CDH7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 620-700
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原理
- Cadherin-7 Polyclonal Antibody
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特异性
- Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Cadherin-7 at AA range: 620-700
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cadherin 7 (CDH7)
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别名
- Cadherin-7
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背景
- Rabbit Anti-Cadherin-7 Polyclonal Antibody,CDH7, CDH7L1, Cadherin-7,CDH7 encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in CDH7 may be associated with bipolar disease in human patients. CDH7 is present in a gene cluster on chromosome 18.,Cadherin-7
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分子量
- observerd band 87kDa
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基因ID
- 1005
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UniProt
- Q9ULB5
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途径
- Cell-Cell Junction Organization
抗原
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