Cadherin 4 抗体 (AA 700-780)
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Quick Overview for Cadherin 4 抗体 (AA 700-780) (ABIN7218856)
抗原
See all Cadherin 4 (CDH4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-780
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原理
- R-cadherin Polyclonal Antibody
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特异性
- R-cadherin Polyclonal Antibody detects endogenous levels of R-cadherin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human R-cadherin at AA range: 700-780
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cadherin 4 (CDH4)
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别名
- R-cadherin
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背景
- Rabbit Anti-R-cadherin Polyclonal Antibody,CDH4, Cadherin-4, Retinal cadherin, R-CAD, R-cadherin,CDH4 is a classical cadherin from the cadherin superfamily. The cadherin 4 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.,Cadherin-4
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基因ID
- 1002
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UniProt
- P55283
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途径
- Cell-Cell Junction Organization, Regulation of Cell Size
抗原
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