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C1r LC (AA 420-500), (Cleaved-Ile464) 抗体

This 兔 多克隆 antibody specifically detects C1r LC in ELISA 和 WB. It exhibits reactivity toward 人.
产品编号 ABIN7212430
发货至: 中国
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Quick Overview for C1r LC (AA 420-500), (Cleaved-Ile464) 抗体 (ABIN7212430)

抗原

C1r LC

适用

宿主

  • 1

克隆类型

  • 1
多克隆

标记

  • 1
非结合性

应用范围

ELISA, Western Blotting (WB)
  • 抗原表位

    AA 420-500, Cleaved-Ile464

    原理

    Cleaved-C1r LC (I464) Polyclonal Antibody

    特异性

    Cleaved-C1r LC (I464) Polyclonal Antibody detects endogenous levels of fragment of activated C1r LC protein resulting from cleavage adjacent to I464.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human C1r LC at AA range: 420-500

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    C1r LC

    背景

    Rabbit Anti-Cleaved-C1r LC (I464) Polyclonal Antibody,C1R, Complement C1r subcomponent, Complement component 1 subcomponent r,C1R (Complement C1r Subcomponent) is a Protein Coding gene. Diseases associated with C1R include immunodeficiency due to an early component of complement deficiency and c1r/c1s deficiency, combined. Among its related pathways are Complement and coagulation cascades and Immune System. GO annotations related to C1R include calcium ion binding and serine-type peptidase activity. An important paralog of C1R is HP.C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.C1R aligns across a gap in the GRCh38 reference genome assembly, and therefore, the 5' end of C1R was annotated on NT_009714.18 and the 3' end was annotated on NT_009759.17 in NCBI's Homo sapiens Annotation Release 106.,Complement C1r subcomponent

    分子量

    observerd band 27kDa

    基因ID

    715

    UniProt

    P00736
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