BTBD6 抗体 (AA 60-140)
Quick Overview for BTBD6 抗体 (AA 60-140) (ABIN7225764)
抗原
See all BTBD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-140
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原理
- BTBD6 Polyclonal Antibody
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特异性
- BTBD6 Polyclonal Antibody detects endogenous levels of BTBD6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human BTBD6 at AA range: 60-140
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BTBD6 (BTB (POZ) Domain Containing 6 (BTBD6))
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别名
- BTBD6
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背景
- Rabbit Anti-BTBD6 Polyclonal Antibody,BTBD6, BDPL, BTB/POZ domain-containing protein 6, Lens BTB domain protein,BTBD6 (BTB/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB/POZ domain and is specifically expressed in the lens. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens.,BTB
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分子量
- observerd band 45kDa
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基因ID
- 90135
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UniProt
- Q96KE9
抗原
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