BCAS3 抗体 (AA 660-740)
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Quick Overview for BCAS3 抗体 (AA 660-740) (ABIN7223322)
抗原
See all BCAS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 660-740
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原理
- BCAS3 Polyclonal Antibody
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特异性
- BCAS3 Polyclonal Antibody detects endogenous levels of BCAS3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human BCAS3 at AA range: 660-740
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))
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别名
- BCAS3
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背景
- Rabbit Anti-BCAS3 Polyclonal Antibody,BCAS3, Breast carcinoma-amplified sequence 3, GAOB1,Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98 % identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23. BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers. It is reported to be a target of metastasis associated protein-1 (MTA-1). Further BCAS3 expression is also upregulated in grade III and IV glioblastomas where it is misexpressed in the tumor cells.,Breast carcinoma-amplified sequence 3
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基因ID
- 54828
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UniProt
- Q9H6U6
抗原
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