BCCIP 抗体 (AA 60-140)
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北京 101111
Quick Overview for BCCIP 抗体 (AA 60-140) (ABIN7223664)
抗原
See all BCCIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-140
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原理
- TOK-1 Polyclonal Antibody
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特异性
- TOK-1 Polyclonal Antibody detects endogenous levels of TOK-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human TOK-1 at AA range: 60-140
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亚型
- IgG
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anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibody
BCCIP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-322) antibodyBCCIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibodyBCCIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 210-314) antibodyBCCIP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) antibodyBCCIP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
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别名
- TOK-1
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背景
- Rabbit Anti-TOK-1 Polyclonal Antibody,BCCIP, TOK1, BRCA2 and CDKN1A-interacting protein, P21- and CDK-associated protein 1, Protein TOK-1,BCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for BCCIP.,BRCA2 and CDKN1A-interacting protein
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分子量
- observerd band 35kDa
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基因ID
- 56647
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UniProt
- Q9P287
抗原
-
