DQB2 抗体
This anti-DQB2 antibody is a 兔 多克隆 antibody detecting DQB2 in ELISA 和 WB. Suitable for 人.
Quick Overview for DQB2 抗体 (ABIN7228290)
抗原
DQB2 (DQB)
(BoLa Class II Histocompatibility Antigen, DQB*0101 beta Chain (DQB))
适用
人
宿主
兔
克隆类型
多克隆
标记
This DQB2 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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原理
- DQB2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DQB2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human DQB2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DQB2 (DQB) (BoLa Class II Histocompatibility Antigen, DQB*0101 beta Chain (DQB))
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别名
- DQB2
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背景
- Rabbit Anti-DQB2 Polyclonal Antibody,HLA class II histocompatibility antigen, DQ beta 2 chain, HLA class II histocompatibility antigen, DX beta chain, MHC class II antigen DQB2,HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.,DQB2
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分子量
- observerd band 29kDa
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基因ID
- 3120
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UniProt
- P05538
抗原
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