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BAG3 抗体 (AA 380-460)

This 兔 多克隆 anti-BAG3 antibody specifically detects BAG3 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7226006
发货至: 中国
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Quick Overview for BAG3 抗体 (AA 380-460) (ABIN7226006)

抗原

See all BAG3 抗体
BAG3 (BCL2-Associated Athanogene 3 (BAG3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This BAG3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 380-460

    原理

    Bag-3 Polyclonal Antibody

    特异性

    Bag-3 Polyclonal Antibody detects endogenous levels of Bag-3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Bag-3 at AA range: 380-460

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    BAG3 (BCL2-Associated Athanogene 3 (BAG3))

    别名

    Bag-3

    背景

    Rabbit Anti-Bag-3 Polyclonal Antibody,BAG3, BIS, BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1,BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by BAG3 (BCL2 associated athanogene 3) contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.,BAG family molecular chaperone regulator 3

    基因ID

    9531

    UniProt

    O95817
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