ATR 抗体 (pSer428)
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北京 101111
Quick Overview for ATR 抗体 (pSer428) (ABIN7223282)
抗原
See all ATR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer428
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原理
- ATR (phospho Ser428) Polyclonal Antibody
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特异性
- Phospho-ATR (S428) Polyclonal Antibody detects endogenous levels of ATR protein only when phosphorylated at S428.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human ATR Phospho-Ser428
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亚型
- IgG
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anti-ATR serine/threonine kinase (ATR) (AA 366-550) antibody
ATR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G6D2 unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2545-2645) antibodyATR 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2545-2644) antibodyATR 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2405-2644) antibodyATR 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (pSer428) antibodyATR 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 1400-1500) antibodyATR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (pSer428) antibodyATR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) antibodyATR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2545-2644) antibodyATR 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (Ser16) antibodyATR 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ATR (ATR serine/threonine kinase (ATR))
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别名
- ATR
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背景
- Rabbit Anti-ATR (phospho Ser428) Polyclonal Antibody,ATR, FRP1, Serine/threonine-protein kinase ATR, Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1,The protein encoded by ATR (ATR serine/threonine kinase) belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of ATR are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.,serine threonine-protein kinase ATR
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基因ID
- 545
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UniProt
- Q13535
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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