ABCA1 抗体
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北京 101111
Quick Overview for ABCA1 抗体 (ABIN7227124)
抗原
See all ABCA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ABCA1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of ABCA1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human ABCA1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
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别名
- ABCA1
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背景
- Rabbit Anti-ABCA1 Polyclonal Antibody,ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, ABC-1, ATP-binding cassette 1, Cholesterol efflux regulatory protein,The membrane-associated protein encoded by ABCA1 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.,ABCA1
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基因ID
- 19
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UniProt
- O95477
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
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