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ACLY 抗体 (pSer455)

This anti-ACLY antibody is a 兔 多克隆 antibody detecting ACLY in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7222670
发货至: 中国

Quick Overview for ACLY 抗体 (pSer455) (ABIN7222670)

抗原

See all ACLY 抗体
ACLY (ATP Citrate Lyase (ACLY))

适用

  • 106
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人, 小鼠, 大鼠, 猴

宿主

  • 95
  • 14

克隆类型

  • 71
  • 38
多克隆

标记

  • 54
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  • 3
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  • 3
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  • 2
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  • 2
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  • 2
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  • 2
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  • 1
  • 1
This ACLY antibody is un-conjugated

应用范围

  • 90
  • 34
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 18
    • 15
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer455

    原理

    ATP-citrate synthase (phospho Ser455) Polyclonal Antibody

    特异性

    Phospho-ATP-citrate synthase (S455) Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein only when phosphorylated at S455.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human ATP-citrate synthase Phospho-Ser455

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ACLY (ATP Citrate Lyase (ACLY))

    别名

    ATP-citrate synthase

    背景

    Rabbit Anti-ATP-citrate synthase (phospho Ser455) Polyclonal Antibody,ACLY, ATP-citrate synthase, ATP-citrate, pro-S-)-lyase, ACL, Citrate cleavage enzyme,ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,ATP-citrate synthase

    基因ID

    47

    UniProt

    P53396

    途径

    Warburg Effect
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