Ataxin 2 抗体 (AA 700-780)
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Quick Overview for Ataxin 2 抗体 (AA 700-780) (ABIN7213706)
抗原
See all Ataxin 2 (ATXN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-780
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原理
- Ataxin-2 Polyclonal Antibody
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特异性
- Ataxin-2 Polyclonal Antibody detects endogenous levels of Ataxin-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Ataxin-2 at AA range: 700-780
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亚型
- IgG
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anti-Ataxin 2 (ATXN2) (AA 775-856) antibody
ATXN2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Internal Region) antibodyVerified ATXN2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 1293-1313), (C-Term) antibodyATXN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 174-383) antibodyATXN2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Internal Region) antibodyATXN2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 321-355) antibodyATXN2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53600 unconjugated
anti-Ataxin 2 (ATXN2) (AA 725-757) antibodyATXN2 适用: 人 WB 宿主: 兔 Polyclonal RB53601 unconjugated
anti-Ataxin 2 (ATXN2) (AA 1214-1313) antibodyATXN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Middle Region) antibodyATXN2 适用: 人, 小鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Center) antibodyATXN2 适用: 人, 猴 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Ataxin 2 (ATXN2)
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别名
- Ataxin-2
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背景
- Rabbit Anti-Ataxin-2 Polyclonal Antibody,ATXN2, ATX2, SCA2, TNRC13, Ataxin-2, Spinocerebellar ataxia type 2 protein, Trinucleotide repeat-containing gene 13 protein,ATXN2 belongs to a group of genes that is associated with microsatellite-expansion diseases, a class of neurological and neuromuscular disorders caused by expansion of short stretches of repetitive DNA. The protein (ataxin 2) encoded by ATXN2 has two globular domains near the N-terminus, one of which contains a clathrin-mediated trans-Golgi signal and an endoplasmic reticulum exit signal. The protein is primarily localized to the Golgi apparatus, with deletion of the Golgi and endoplasmic reticulum signals resulting in abnormal subcellular localization. In addition, the N-terminal region contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues. Intermediate length expansions of this tract increase susceptibility to amyotrophic lateral sclerosis, while long expansions of this tract result in spinocerebellar ataxia-2, an autosomal-dominantly inherited, neurodegenerative disorder. Alternative splicing results in multiple transcript variants.,Ataxin-2
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基因ID
- 6311
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UniProt
- Q99700
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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