APITD1 抗体 (AA 70-150)
Quick Overview for APITD1 抗体 (AA 70-150) (ABIN7227850)
抗原
See all APITD1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 70-150
-
原理
- CENPS Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of CENPS protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human CENPS protein at AA range: 70-150
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))
-
别名
- CENPS
-
背景
- Rabbit Anti-CENPS Polyclonal Antibody,Centromere protein S, CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-associated histone fold protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa,CENPS (Centromere Protein S) was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. CENPS was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants.,CENPS
-
分子量
- observerd band 15kDa
-
基因ID
- 100526739
-
UniProt
- Q8N2Z9
抗原
-