AIFM3 抗体 (AA 10-90)
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Quick Overview for AIFM3 抗体 (AA 10-90) (ABIN7213510)
抗原
See all AIFM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- AIFL Polyclonal Antibody
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特异性
- AIFL Polyclonal Antibody detects endogenous levels of AIFL protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human AIFL at AA range: 10-90
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亚型
- IgG
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 216-265) antibody
AIFM3 适用: 人, Cow, 豚鼠, 兔, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 10-59) antibodyAIFM3 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (N-Term) antibodyAIFM3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (Middle Region) antibodyAIFM3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
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别名
- AIFL
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背景
- Rabbit Anti-AIFL Polyclonal Antibody,AIFM3, AIFL, Apoptosis-inducing factor 3, Apoptosis-inducing factor-like protein,AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.,Apoptosis-inducing factor 3
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基因ID
- 150209
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UniProt
- Q96NN9
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途径
- Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
抗原
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