Apoptosis Inhibitor 5 抗体 (AA 390-470)
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Quick Overview for Apoptosis Inhibitor 5 抗体 (AA 390-470) (ABIN7213626)
抗原
See all Apoptosis Inhibitor 5 (API5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-470
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原理
- API5 Polyclonal Antibody
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特异性
- API5 Polyclonal Antibody detects endogenous levels of API5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human API5 at AA range: 390-470
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Apoptosis Inhibitor 5 (API5)
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别名
- API5
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背景
- Rabbit Anti-API5 Polyclonal Antibody,API5, MIG8, Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, AAC-11, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL,API5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,Apoptosis inhibitor 5
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基因ID
- 8539
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UniProt
- Q9BZZ5
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途径
- Growth Factor Binding
抗原
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