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AMH 抗体 (AA 380-460)

This 兔 多克隆 anti-AMH antibody specifically detects AMH in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7229680
发货至: 中国
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Quick Overview for AMH 抗体 (AA 380-460) (ABIN7229680)

抗原

See all AMH 抗体
AMH (Anti-Mullerian Hormone (AMH))

适用

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人, 小鼠, 大鼠

宿主

  • 84
  • 51
  • 1
  • 1
  • 1

克隆类型

  • 81
  • 57
多克隆

标记

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This AMH antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 12
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    • 3
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    • 1
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    • 1
    AA 380-460

    原理

    MIS Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of MIS protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human MIS protein at AA range: 380-460

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    AMH (Anti-Mullerian Hormone (AMH))

    别名

    MIS

    背景

    Rabbit Anti-MIS Polyclonal Antibody,Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS,AMH encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.,MIS

    分子量

    observerd band 61kDa

    基因ID

    268

    UniProt

    P03971

    途径

    Negative Regulation of Hormone Secretion
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