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ANKRD30A 抗体 (AA 1010-1090)

The 兔 多克隆 anti-ANKRD30A antibody is suitable to detect ANKRD30A in samples from 人. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN7213582
发货至: 中国
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Quick Overview for ANKRD30A 抗体 (AA 1010-1090) (ABIN7213582)

抗原

ANKRD30A (Ankyrin Repeat Domain 30A (ANKRD30A))

适用

宿主

  • 5
  • 1

克隆类型

  • 5
  • 1
多克隆

标记

  • 6
This ANKRD30A antibody is un-conjugated

应用范围

  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 2
    • 2
    • 1
    AA 1010-1090

    原理

    Rabbit Anti-ANKRD30A Polyclonal Antibody

    特异性

    ANKRD30A Polyclonal Antibody detects endogenous levels of ANKRD30A protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the C-terminal region of human ANKRD30A at AA range: 1010-1090

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    ANKRD30A (Ankyrin Repeat Domain 30A (ANKRD30A))

    别名

    ANKRD30A

    背景

    ANKRD30A, Ankyrin repeat domain-containing protein 30A, Serologically defined breast cancer antigen NY-BR-1Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD30A (ankyrin repeat domain 30A), also known as serologically defined breast cancer antigen NY-BR-1, is a 1,397 amino acid coiled-coil protein. Containing six ANK repeats and thirty-seven exons, ANKRD30A is a distant homolog of the POTE family. Initiated by either Dnmt1 or Met-57, ANKRD30A is highly expressed in breast and testis, and faintly in placenta. Present in 80 % of breast cancers, but not in other types of tumors, ANKRD30A is a differentiation antigen and a potential target for antibody-based therapies in breast cancers.

    分子量

    153kD

    基因ID

    91074

    UniProt

    Q9BXX3
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