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beta Amyloid 抗体 (AA 221-270)

This 兔 多克隆 anti-beta Amyloid antibody specifically detects beta Amyloid in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7226828
发货至: 中国
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Quick Overview for beta Amyloid 抗体 (AA 221-270) (ABIN7226828)

抗原

See all beta Amyloid (Abeta) 抗体
beta Amyloid (Abeta) (Amyloid beta (Abeta))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This beta Amyloid antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 221-270

    原理

    Amyloid-β Polyclonal Antibody

    特异性

    Amyloid-β Polyclonal Antibody detects endogenous levels of Amyloid-β.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from Amyloid-beta at AA range: 221-270

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    beta Amyloid (Abeta) (Amyloid beta (Abeta))

    别名

    Amyloid-beta

    背景

    Rabbit Anti-Amyloid-β Polyclonal Antibody,amyloid beta (A4) precursor protein,APP (amyloid beta precursor protein) encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in APP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for APP.,Amyloid-β

    基因ID

    351

    UniProt

    P05067

    途径

    Inflammasome
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