Aminoacylase 1 抗体
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北京 101111
Quick Overview for Aminoacylase 1 抗体 (ABIN7227208)
抗原
See all Aminoacylase 1 (ACY1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-ACY1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of ACY1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human ACY1 protein
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亚型
- IgG
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anti-Aminoacylase 1 (ACY1) (AA 1-408) antibody
ACY1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 4F1-B7 unconjugated
anti-Aminoacylase 1 (ACY1) (AA 2-408) antibodyACY1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminoacylase 1 (ACY1) antibodyACY1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Aminoacylase 1 (ACY1) antibodyACY1 适用: 人, 犬, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Aminoacylase 1 (ACY1) (AA 1-408) antibodyACY1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aminoacylase 1 (ACY1) (AA 1-408) antibodyACY1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aminoacylase 1 (ACY1) antibodyACY1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Aminoacylase 1 (ACY1) (AA 1-409) antibodyACY1 适用: 人 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 4F1-B7 unconjugated
anti-Aminoacylase 1 (ACY1) (AA 1-408) antibodyACY1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aminoacylase 1 (ACY1) antibodyKD Validated ACY1 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB3810 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Aminoacylase 1 (ACY1)
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别名
- ACY1
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背景
- N-acyl-L-amino-acid amidohydrolaseACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 is located on chromosome 3p21. , a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in ACY1 cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between ACY1 and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID: 100526760. A related pseudogene has been identified on chromosome 18.
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分子量
- 44kD
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基因ID
- 95
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UniProt
- Q03154
抗原
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