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Aminoacylase 1 抗体

This 兔 多克隆 anti-Aminoacylase 1 antibody specifically detects Aminoacylase 1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7227208
发货至: 中国
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Quick Overview for Aminoacylase 1 抗体 (ABIN7227208)

抗原

See all Aminoacylase 1 (ACY1) 抗体
Aminoacylase 1 (ACY1)

适用

  • 36
  • 15
  • 4
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 23
  • 14
  • 2

克隆类型

  • 25
  • 14
多克隆

标记

  • 32
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aminoacylase 1 antibody is un-conjugated

应用范围

  • 29
  • 16
  • 12
  • 8
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    ACY1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of ACY1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human ACY1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Aminoacylase 1 (ACY1)

    别名

    ACY1

    背景

    Rabbit Anti-ACY1 Polyclonal Antibody,N-acyl-L-amino-acid amidohydrolase,ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 is located on chromosome 3p21. , a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in ACY1 cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between ACY1 and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID: 100526760. A related pseudogene has been identified on chromosome 18.,ACY1

    基因ID

    95

    UniProt

    Q03154
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