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alpha 1 Sodium Potassium Atpase (pTyr260) 抗体

The 兔 多克隆 anti-alpha 1 Sodium Potassium Atpase antibody is suitable to detect alpha 1 Sodium Potassium Atpase in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7231444
发货至: 中国
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Quick Overview for alpha 1 Sodium Potassium Atpase (pTyr260) 抗体 (ABIN7231444)

抗原

alpha 1 Sodium Potassium Atpase

适用

人, 小鼠, 大鼠

宿主

  • 2
  • 1

克隆类型

  • 2
  • 1
多克隆

标记

  • 3
非结合性

应用范围

  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 2
    • 1
    pTyr260

    原理

    Rabbit Anti-Sodium Potassium ATPase alpha-1 (Phospho-Tyr260) Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of Sodium Potassium ATPase alpha-1 when Phospho occurs at Tyr260

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human Sodium Potassium ATPase alpha-1 (Phospho-Tyr260) Antibody protein at AA range: 230-290

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    alpha 1 Sodium Potassium Atpase

    别名

    Sodium Potassium ATPase alpha-1

    背景

    Sodium/potassium-transporting ATPase subunit alpha-1, Na(+/K(+ ATPase alpha-1 subunit, Sodium pump subunit alpha-1The protein encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. ATP1A1 encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for ATP1A1.

    分子量

    115kD

    基因ID

    476

    UniProt

    P05023
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