ACER1 抗体 (AA 100-180)
Quick Overview for ACER1 抗体 (AA 100-180) (ABIN7226610)
抗原
See all ACER1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-180
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原理
- ASAH3 Polyclonal Antibody
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特异性
- ASAH3 Polyclonal Antibody detects endogenous levels of ASAH3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180
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亚型
- IgG
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anti-Alkaline Ceramidase 1 (ACER1) (Internal Region) antibody
ACER1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 1 (ACER1) (Internal Region) antibodyACER1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 1 (ACER1) antibodyACER1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 1 (ACER1) (AA 141-190) antibodyACER1 适用: 人, 猴, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 1 (ACER1) (C-Term) antibodyACER1 适用: 人, 大鼠, Cow, 豚鼠, 兔, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ACER1 (Alkaline Ceramidase 1 (ACER1))
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别名
- ASAH3
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背景
- Rabbit Anti-ASAH3 Polyclonal Antibody,ACER1, ASAH3, Alkaline ceramidase 1, AlkCDase 1, Alkaline CDase 1, Acylsphingosine deacylase 3, N-acylsphingosine amidohydrolase 3,Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 (alkaline ceramidase 1) is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine.,Alkaline ceramidase 1
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基因ID
- 125981
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UniProt
- Q8TDN7
抗原
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