AGXT2 抗体 (AA 340-420)
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北京 101111
Quick Overview for AGXT2 抗体 (AA 340-420) (ABIN7227242)
抗原
See all AGXT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-420
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原理
- Rabbit Anti-AGT2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of AGT2 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human AGT2 protein at AA range: 340-420
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))
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别名
- AGT2
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背景
- Alanine--glyoxylate aminotransferase 2, mitochondrial, AGT 2, (R)-3-amino-2methylpropionate--pyruvate transaminase, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, D-AIBATThe protein encoded by AGXT2 is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in AGXT2 affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants.
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分子量
- 56kD
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基因ID
- 64902
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UniProt
- Q9BYV1
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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