RAGE 抗体 (AA 133-182)
Our Local Distributor
北京 101111
Quick Overview for RAGE 抗体 (AA 133-182) (ABIN7220064)
抗原
See all RAGE (AGER) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 133-182
-
原理
- Rabbit Anti-RAGE Polyclonal Antibody
-
特异性
- RAGE Polyclonal Antibody detects endogenous levels of RAGE protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from the Internal region of human RAGE at AA range: 133-182
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
-
别名
- RAGE
-
背景
- AGER, RAGE, Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end productsThe advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID: 18089847).
-
分子量
- 37kD
-
基因ID
- 177
-
UniProt
- Q15109
-
途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
抗原
-