ADD3 抗体 (AA 400-480)
Our Local Distributor
北京 101111
Quick Overview for ADD3 抗体 (AA 400-480) (ABIN7213494)
抗原
See all ADD3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 400-480
-
原理
- Adducin γ Polyclonal Antibody
-
特异性
- Adducin γ Polyclonal Antibody detects endogenous levels of Adducin γ protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human Adducin gamma at AA range: 400-480
-
亚型
- IgG
-
-
anti-Adducin 3 (Gamma) (ADD3) (AA 462-560) antibody
ADD3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (C-Term) antibodyADD3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, 斑马鱼 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (C-Term) antibodyADD3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, 斑马鱼, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (C-Term) antibodyADD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- ADD3 (Adducin 3 (Gamma) (ADD3))
-
别名
- Adducin gamma
-
背景
- Rabbit Anti-Adducin γ Polyclonal Antibody,ADD3, ADDL, Gamma-adducin, Adducin-like protein 70,Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known.,Gamma-adducin
-
基因ID
- 120
-
UniProt
- Q9UEY8
抗原
-
