ABHD12 抗体 (AA 200-280)
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Quick Overview for ABHD12 抗体 (AA 200-280) (ABIN7213428)
抗原
See all ABHD12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-280
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原理
- ABHD12 Polyclonal Antibody
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特异性
- ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human ABHD12 at AA range: 200-280
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))
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别名
- ABHD12
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背景
- Rabbit Anti-ABHD12 Polyclonal Antibody,ABHD12, C20orf22, Monoacylglycerol lipase ABHD12, 2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 12,ABHD12 encodes an enzyme (abhydrolase domain containing 12) that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in ABHD12 are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for ABHD12.,Monoacylglycerol lipase ABHD12
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基因ID
- 26090
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UniProt
- Q8N2K0
抗原
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