ABL1/2 抗体
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北京 101111
Quick Overview for ABL1/2 抗体 (ABIN7213438)
抗原
See all ABL1/2 (ABL1/ABL2) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Abl1/2 Polyclonal Antibody
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特异性
- Abl1/2 Polyclonal Antibody detects endogenous levels of Abl1/2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Abl1/2 around the non-phosphorylation site of Y393/439
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亚型
- IgG
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anti-Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2) (Lys5) antibody
ABL1/ABL2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2) (C-Term), (pTyr393), (pTyr439) antibodyABL1/ABL2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2) (Tyr393), (Tyr429) antibodyABL1/ABL2 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
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别名
- Abl1/2
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背景
- Rabbit Anti-Abl1/2 Polyclonal Antibody,ABL1, ABL, JTK7, Tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150, ABL2, ABLL, ARG, Abelson tyrosine-protein kinase 2, Abelson murine leukemia vira,ABL1 is a protooncogene that encodes a protein tyrosine kinase (ABL proto-oncogene 1, non-receptor tyrosine kinase) involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. ABL1 has been found fused to a variety of translocation partner genes in various leukemias, most notably the t (9,22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR, MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.,Tyrosine-protein kinase ABL1
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基因ID
- 25, 27
抗原
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