ADCK5 抗体 (AA 120-200)
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北京 101111
Quick Overview for ADCK5 抗体 (AA 120-200) (ABIN7213488)
抗原
See all ADCK5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-200
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原理
- ADCK5 Polyclonal Antibody
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特异性
- ADCK5 Polyclonal Antibody detects endogenous levels of ADCK5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human ADCK5 at AA range: 120-200
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亚型
- IgG
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anti-AarF Domain Containing Kinase 5 (ADCK5) (N-Term) antibody
ADCK5 适用: 人, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-AarF Domain Containing Kinase 5 (ADCK5) (AA 434-464), (C-Term) antibodyADCK5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8211 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ADCK5 (AarF Domain Containing Kinase 5 (ADCK5))
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别名
- ADCK5
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背景
- Rabbit Anti-ADCK5 Polyclonal Antibody,ADCK5, Uncharacterized aarF domain-containing protein kinase 5,CABC1 (chaperone activity of bc1 complex-like), also known as COQ8 or ADCK3 (aarF domain-containing protein kinase 3) is a 647 amino acid mitochondrial protein that belongs to the ADCK protein kinase. Ubiquitously expressed with higher expression in heart and skeletal muscle, CABC1 is thought to function as a chaperone in the proper assembly of protein complexes found in the respiratory chain. CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53. When CABC1 expression is inhibited, p53-induced apoptosis is partially suppressed, suggesting a possible role for CABC1 in tumor suppression. Mutations in the gene encoding CABC1 may be implicated in ubiquinone deficiency which can lead to cerebellar ataxia and seizures. Four isoforms of CABC1 exist due to alternative splicing events. Other members of the ADCK protein kinase family include ADCK1, ADCK2, ADCK4 and ADCK5.,Uncharacterized aarF domain-containing protein kinase 5
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基因ID
- 203054
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UniProt
- Q3MIX3
抗原
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