PFKFB2 抗体 (pSer483)
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北京 101111
Quick Overview for PFKFB2 抗体 (pSer483) (ABIN7213270)
抗原
See all PFKFB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer483
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原理
- PFK-2 car (phospho Ser483) Polyclonal Antibody
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特异性
- Phospho-PFK-2 car (S483) Polyclonal Antibody detects endogenous levels of PFK-2 car protein only when phosphorylated at S483.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human PFK-2 car Phospho-Ser483
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亚型
- IgG
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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 360-505) antibody
PFKFB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 446-505) antibodyPFKFB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 467-497), (C-Term) antibodyPFKFB2 适用: 人 WB 宿主: 兔 Polyclonal RB4033 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (pSer483) antibodyPFKFB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (pSer483) antibodyPFKFB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) antibodyPFKFB2 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, 豚鼠, 兔, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 336-385) antibodyPFKFB2 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) antibodyPFKFB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 4-505) antibodyPFKFB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 1-30), (N-Term) antibodyPFKFB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4031-4032 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
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别名
- PFK-2 car
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背景
- Rabbit Anti-PFK-2 car (phospho Ser483) Polyclonal Antibody,PFKFB2, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2, 6PF-2-K/Fru-2,6-P2ase 2, PFK/FBPase 2, 6PF-2-K/Fru-2,6-P2ase heart-type isozyme,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 encoded by PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for PFKFB2.,6-phosphofructo-2-kinase
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分子量
- observerd band 58kDa
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基因ID
- 5208
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UniProt
- O60825
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途径
- PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
抗原
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