3beta-HSD7 (AA 90-170) 抗体
This anti-3beta-HSD7 antibody is a 兔 多克隆 antibody detecting 3beta-HSD7 in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7213382
发货至:
中国
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Quick Overview for 3beta-HSD7 (AA 90-170) 抗体 (ABIN7213382)
抗原
3beta-HSD7
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 90-170
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原理
- 3β-HSD7 Polyclonal Antibody
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特异性
- 3β-HSD7 Polyclonal Antibody detects endogenous levels of 3β-HSD7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human 3beta-HSD7 at AA range: 90-170
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亚型
- IgG
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anti-3beta-HSD7 (Internal Region) antibody
适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- 3beta-HSD7
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背景
- Rabbit Anti-3β-HSD7 Polyclonal Antibody,HSD3B7, 3 beta-hydroxysteroid dehydrogenase type 7, 3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-HSD VII, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase, C(27) 3-beta-HSD, Cholest-5-ene-3-beta, 7-alpha-diol 3-beta-dehydrogenase,HSD3B7 encodes an enzyme (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7) which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in HSD3B7 are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for HSD3B7.,3 beta-hydroxysteroid dehydrogenase type 7
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基因ID
- 80270
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UniProt
- Q9H2F3
抗原
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