HAAO 抗体 (AA 30-110)
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北京 101111
Quick Overview for HAAO 抗体 (AA 30-110) (ABIN7227096)
抗原
See all HAAO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- Rabbit Anti-3HAO Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of 3HAO protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human 3HAO protein at AA range: 30-110
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亚型
- IgG
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anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) antibody
HAAO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 153-223) antibodyHAAO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) antibodyHAAO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 101-200) antibodyHAAO 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 72-121) antibodyHAAO 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (N-Term) antibodyHAAO 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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别名
- 3HAO
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背景
- 3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HADHAAO (3-Hydroxyanthranilate 3,4-Dioxygenase) is a Protein Coding gene. Among its related pathways are Metabolism and superpathway of tryptophan utilization. 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
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分子量
- 31kD
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基因ID
- 23498
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UniProt
- P46952
抗原
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